General Cell Based Assays
Eurofins Discoverx PathHunter eXpress HRH3 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0509E2CP2L)
The PathHunter HRH3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. histamine) based activation of HRH3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HRH3 and EA-tagged β-Arrestin-2. Activation of HRH3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter™ Human LPA1 (EDG2) Gi/Gq cAMP Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human LPA1 (EDG2) Gi/Gq Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure EDG2 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CTACK (CCR10) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human CTACK (CCR10) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure CCR10 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress mEDNRA CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0685E2MCP0M)
The PathHunter mEDNRA eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. endothelin-1) based activation of mEDNRA GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mEDNRA and EA-tagged β-Arrestin-2. Activation of mEDNRA stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Sigma Aldrich Fine Chemicals Biosciences Lactate Oxidase from Aeroc
LACTATE Lactate Oxidase from Aeroc
Molecular Devices Fatty Acid Uptake Assay Kit, Homogeneous, Fluorescence, 96/384-Well
The QBT Fatty Acid Uptake Assay Kit is a homogeneous, fluorescence-based assay for rapid, real-time measurement of fatty acid uptake in live cells. It uses a BODIPY-dodecanoic acid fluorescent analog with quench technology and is configured for high-throughput screening in 96- and 384-well microplates.
- One-step homogeneous fluorescence assay using a BODIPY-dodecanoic acid analog.
- Proprietary quench-based format for real-time fatty acid uptake monitoring.
- Evaluation kit contains 2 vials, sufficient for two microplates.
- Compatible with 96-well and 384-well microplate formats and bottom-read detection.
- Designed for high-throughput screening of fatty acid transporters and uptake inhibitors.
Eurofins Discoverx PathHunter Human F2R β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human F2R β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure F2R (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human MLNR β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human MLNR β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure MLNR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human IkB Degradation Cell-Based Assay Kit (HEK 293)
The PathHunter Human IkB Degradation Stable Cell Line Assay (HEK 293) measures pathway activation-induced degradation of IκB target protein. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Echelon Biosciences Research Labs High Throughput Autotaxin Inhibitor Screening Kit
The Autotaxin Inhibitor Screening Kit utilizes purified autotaxin (ATX) and the autotaxin substrate FS-3, which fluoresces upon cleavage. The assay is performed in a 96 well plate and quantifies the autotaxin activity in the presence of the users samples by measuring changes in fluorescence over time.Sample Type: Inhibitors against ATXSample Volume: 10 L/ well of your sample compoundsSample Considerations: Some organic solvents interfere with the assay (see technical data sheet). This item is non returnable
Eurofins Discoverx AssayComplete Cell Plating 24 Reagent, 500. (93-0563R24B)
AssayComplete Cell Plating 24 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 500 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter Human TACR2 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human TACR2 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure TACR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human Oncostatin M (OSMR/IL6ST) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human Oncostatin M (OSMR/IL6ST) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of OSMR/IL6ST. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress SCTR CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0237E2CP0M)
The PathHunter SCTR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. secretin) based activation of SCTR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SCTR and EA-tagged β-Arrestin-2. Activation of SCTR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery R-PLEX Human ACE2 ASY
The R-PLEX Human ACE2 Assay from Meso Scale Diagnostics is a multiplex immunoassay that measures human angiotensin-converting enzyme 2 (ACE2) levels in serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements The assay can help monitor ACE2 levels which may be relevant in COVID-19 infection and research This 10-plex assay includes a total of 10 analytes including human ACE2 and 9 other biomarkers